KATTALAR VA BOLALARDA SURUNKALI GEPATIT C NI DAVOLASH IMKONIYATLARI VA ISTIQBOLLARI
Keywords:
surunkali gepatit C, bolalar, interferon, pegilatlangan interferon, proteaz ingibitorlari, nukleos(t)id va nukleos(t)id bo'lmagan ingibitorlar.Abstract
Surunkali gepatit C (standart IFN-a, PEG-IFN-a, ribaverin) bilan og'rigan bolalar va kattalarda antivirus terapiyaning rivojlanish bosqichlari izchil tavsiflangan. Asosiy e'tibor klinisislar duch keladigan zamonaviy muammolar va istiqbollar antivirus dorilarning yangi guruhlari – nukleozid analoglari, shu jumladan so'nggi avlod, virus kodlari blokerlari, molekulyar darajada ishlaydigan dorilar yaratilishiga qaratilgan. Bu o’z navbatida virus replikatsiyasi va gen ekspressiyasi to'liq tormozlashni ta'minlaydi va kelajakda eng istiqbolli yo’l hisoblanadi.
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