SURGICAL TREATMENT OF DRUG-RESISTANT EPILEPSY ( LITERATURE REVIEW )
Abstract
The article is devoted to a relatively rare hereditary neurocutaneous disease - Sturge -Weber syndrome. Modern ideas about epidemiology, etiopathogenesis , clinical manifestations and the concept of surgical treatment of a disease accompanied by epileptic seizures are outlined. An analysis of the results of treatment of 21 patients (age from 1 to 11 years) with Sturge -Weber syndrome for the period from 1996 to 2016 was carried out. 10 patients (age from 18 months to 10 years) were operated on, in five cases hemispherotomy was performed , in another five, multifocal resection was performed. Favorable results of surgical treatment were achieved ( Engel outcome I, II) in 70% of cases. Lack of positive dynamics or further progression of the disease was noted in two patients; one child died as a result of sudden death due to epilepsy. Of the non-operated children (age from 2 to 5 years), during the observation period, improvement against the background of anticonvulsant polytherapy was noted in six patients, no changes in the course of the disease were established in three cases, and in three observations there was further progression of epilepsy. An analysis of two clinical cases was carried out, the results were compared with literature data.
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