The Role of Cytokines in the Formation of Cervical Cancer

Abstract

Cervical cancer is one of the most common forms of cancer in women in the world. The carcinogenesis of breast cancer proceeds for 10-30 years against the background of persistent HPV infection of high oncogenic risk and passes the stages of CIN I, II and III degrees. Currently, much attention is being paid to CIN screening for the prevention of cervical cancer. Numerous studies are being conducted to assess specificity of neoplastic cell staining at different degrees of CIN in cervical tissues and cytological samples. Of great importance for the identification of such markers is the study of the mechanisms and signaling pathways involved in the formation and progression of intraepithelial neoplasia to breast cancer in women. The review article discusses the main mechanisms and targets involved in the carcinogenesis of breast cancer. Promising markers for the diagnosis of CIN are considered.