The Zone of Transformation and Risk of New Formations in the Epithelial Cover of the Cervix
Abstract
The origin and development of pathology is influenced by the peculiarities of the structure of the uterus, the state and relationship of the epithelial layers of the ectocervix (the part of the cervix located in the vagina). The transformation zone (the place of transition of the squamous epithelium of the ectocervix into the cylindrical epithelium of the endocervix (cervical canal)) is subject to the most frequent changes. The junction zone at the reproductive age is located in the area of the external throat of the cervix. However, it can shift, the reasons for which are the effects of hormones, injuries, inflammatory processes, etc. With the onset of menopausal age, the vagina atrophies and deforms, which leads to the lifting of the docking zone into the cervical canal. The vast majority of cases of malignant neoplasms were noted in the squamous epithelium and only a small part (no more than 3-5%) – in the cylindrical epithelial cells of the cervical canal.
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